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Automated home cage analyses, live imaging and treatment”. Institute of Molecular Genetics ASCR Videnska 1 20 Prague Czech Repulic The Institute for Molecular Genetics IMG currently hosts 24 research groups with over scientists dealing with topics covering molecular and cellular immunology, molecular and cellular oncology, cell biology of the nucleus and cytoskeleton, functional genomics and bioinformatics, study of oncogenes, molecular biology of development, structural biology and mechanisms of receptor signaling. As a major international research centre, the MGU is at the forefront of mouse genetics and functional genomic research. Comprising 9 faculties, 24 Schools and departments, the university has over one hundred research centers and institutes. ICS is equipped with integrated facilities for genetics, cellular and molecular biology, and notably for creation and characterization of genetically engineered mouse models and their behaviour and cognitive assessments. The Mouse Imaging Centre MICe provides collaborative access to state-of-the-art digital imaging technologies, including magnetic resonance microscopy MRM , micro-computed tomography, and optical projection tomography for the morphological analysis of mutant mice. The animal facilities at the Helmholtz Center for Infection Research HZI currently provide space for animal breeding with a total capacity of 19, cages, including a dedicated infection unit to perform experiments at the biosafety level BSL2.

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The institute has ample expertise in mouse pathology and an established record in studying drug resistance mechanisms in mouse models of human cancer. KI has a large core facility for production, uardity and hardiyt of genetically modified mice. The Institute for Molecular Genetics IMG currently hosts 24 research groups with over scientists dealing with topics covering molecular and cellular immunology, molecular and cellular oncology, cell biology of the nucleus and cytoskeleton, functional genomics and bioinformatics, study of oncogenes, molecular biology of development, structural biology and mechanisms of receptor signaling.

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A transmembrane prolyl 4-hydroxylase is a fourth ic-850 4-hydroxylase regulating erythropoietin production and erythropoiesis. The Laboratory has five units: The CNB annual budget is 42 million Euros with projects executed inincluding 26 from the EC and 27 from biotech companies and hardiyt foundations, that resulted in publications with a mean IF of 5, Jean-Pierre Gorvel has also expertise in approaches aiming at imaging of hxrdity processes in vivo. CIPHE comprises a knockin-knockout booster unit, a microinjection and cryopreservation unit, an immunophenotyping unit, a BSL3 facility capable of live imaging of infectious processes, and a EOPS animal facility.

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Thomas Budiman, a physicist and division manager of Inhalation and Metabolism, involved in the development of new techniques and products, technical consulting for pre- and after-sales as well as responsible for after-sales service.

Furthermore, all the necessary mouse technologies such as generation of Knock-Out strains, re-derivation of imported mouse strains by embryo transfer, freezing of mouse strains for storage, and in vitro fertilization are available.

Boca Raton, London, New York.

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Mechanistic basis of infertility of mouse intersubspecific hybrids. CIPHE is in the process of building long-term collaboration with leading research institutes worldwide and will reinforce cooperation with industrial pharmaceutical partners.

Institute of Molecular Genetics ASCR Videnska 1 20 Prague Czech Repulic The Institute for Molecular Genetics IMG currently hosts 24 research groups with over scientists dealing with topics covering molecular and cellular immunology, molecular and cellular oncology, cell biology of the nucleus and cytoskeleton, functional genomics and bioinformatics, study of oncogenes, molecular biology of development, structural biology and mechanisms of receptor signaling.

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes.

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The IGC mouse facility is partitioned into 5 independent areas, each with a specific bio-containment level, including germ-free and strict SPF. While this type of work on individual genes will continue, we want to shift it more towards harditt addressing gene function post-natally, including in adult somatic stem cells and cells of their niche, with emphasis on developmental signaling and its nuclear interpretation, in neurodevelopment and neuropathology.

Tel Aviv University P. Production and experimental areas harduty set to serve active research in hxrdity fields of biology development, neurobiology, infectious diseases, immunology, genetics. Fleming is housed in a 6. Curr Pharm Biotechnol She is actively involved in the generation of transgenic mice, rederivation of contaminated strains, cryopreservation and revitalization of archived mouse models. At least strains are subject to a standard phenotypic analysis per year.

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Anna Pujol, highly specialized technician, expertise in mouse mutagenesis, generation of transgenic and knock-out mice; Prof.

The University of Oulufounded inis an international science university which creates innovation for the future, well-being, and knowledge through multidisciplinary research and education. Fatima Bosch, is specialized in the study of the pathophysiology of metabolic diseases, especially diabetes mellitus and obesity, and their secondary complications retinopathy, nephropathy and neuropathy.

Generation of mice with a conditional Stat1 null allele. Radislav Sedlacek generated and analyzed a number of mouse models to reveal functions of proteolytic enzymes. Mouse large-scale phenotyping initiatives: Sylvie Franckhauser, Research Associate, expertise in somatic mutagenesis, ic580 and metabolism; Dr. The research laboratory covers all major areas of oncology research, with special emphasis on mouse tumor models, cell based screens, and translational research.

In addition, he has experience in the genetic mapping and positional cloning of mouse mutations.

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ROS implication in a new antitumor strategy based on non-thermal plasma. Nat Struct Mol Biol. Kontoyiannis Mouse resource enquiries: The Harcity has contributed to archiving and distribution of mutant mice under all the EMMA funded projects with a high level profile for distribution inside the network.

New laboratories designed and dedicated for these activities started operation in and were upgraded in to serve as the Finnish EMMA node.